UC-II Collagen

UC-II Collagen

Our triple action UC-II® Collagen with Manganese and Vitamin C works with the immune system to support healthy cartilage, aid joint comfort and maintain long term mobility. This advanced formula delivers results with just 1 small capsule per day.

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Product information

Overview

UC-II Collagen


Advanced joint collagen, clinically proven

The perfect partner to our entire canine range, UC-II® collagen provides a powerful additional layer of joint support. This clinically studied ingredient helps maintain healthy cartilage, supports strong and flexible joints, and aids everyday recovery at just 40mg per day.

Unlike standard bovine and marine collagen supplements, UC-II® is a unique form of undenatured Type II collagen that works through a completely different and far more targeted biological pathway. We combine it with manganese and Vitamin C to enhance and maximise joint support.

How does UC-II® work?

UC-II® collagen works via a process called oral tolerance, a natural immune system response that supports joint health from within.

As we age, the immune system can become over reactive and begin to mistakenly target the body’s own cartilage. This low grade immune activity contributes to stiffness, discomfort and cartilage breakdown over time.

When undenatured Type II collagen is taken orally, it interacts with immune cells in the gut. This helps “re-educate” the immune system so it becomes less reactive towards joint cartilage. Clinical studies show that UC-II® collagen can significantly:

  • Reduce joint discomfort
  • Improve joint function
  • Provide long-term cartilage protection

This effect is seen at just 40mg per day, making it one of the most efficient collagen supplements for joint care. Our Hydrolysed Type 2 collagen powder provides the raw building blocks for cartilage whilst UC-II® helps protect what you already have, making them the perfect partners.

Why Type II Collagen Matters?

There are three main types of collagen in the body:

  • Type I – supports skin, hair and connective tissue
  • Type II – supports joints and cartilage
  • Type III – supports skin and muscle structure

Articular cartilage is made up of approximately 85–90% Type II collagen.
This makes Type II collagen the most important and most effective form for targeted joint support.

Unlike marine or bovine collagen (Types I and III), which are used in much larger doses for skin and beauty, Undenatured UC-II® collagen is required in very small amounts to influence joint health because it works through immune regulation rather than gut absorption.

What makes UC-II different?

UC-II® is a patented, clinically studied form of undenatured Type II collagen, naturally sourced from chicken cartilage and processed at very low temperatures to preserve its structure.

“Undenatured” means the collagen maintains its three-dimensional structure, which is essential for triggering oral tolerance. This makes UC-II® a valuable part of joint support alongside our Hydrolysed Type 2 collagen powder.

Why joints change with age?


As dogs get older, the body produces less collagen and the collagen it does produce is lower in quality. Cartilage becomes weaker, and recovery slows, which can lead to:

  • Stiff, achy joints
  • Reduced mobility
  • Slower recovery after activity

UC-II® works to help protect cartilage, support joint comfort, and maintain mobility as part of a comprehensive joint care regime.

Why choose this product?

  • Scientifically proven to support joint comfort
  • Scientifically proven to aid mobility
  • Supports cartilage regeneration
  • Aids everyday recovery
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A word from Kate

"I believe everyone deserves the very best in Joint Care. And so I created it! I chose to put quality & effectiveness before profit margins. I chose to never waiver from my ethos. I chose dedication to what I believe in so that I could help others. It’s been so worth it!"

- Kate Williams, Founder of Riaflex

Frequently asked questions

Can Riaflex joint support be used with prescription only medicine?

Our supplements can be used alongside most prescription only medicines (with the exception of Devils Alternative & Boswellia in certain cases). We haven't extensively tested our supplements with all medications so we recommend checking with your vet first. If you have specific questions about certain medications and what supplements you can use from our range then please contact our customer care team before purchasing, on 01275 627885 or email contact@riaflex.co.uk.

What age can I start feeding joint supplements to my dog?

You can start giving your dog a joint supplement as soon as they're able to eat solid food, typically around 8 weeks old. The key is to give them the right one for their age and needs. Riaflex joint care range, offers supplements for Young Dogs, Working dogs, and those who need extra support.

Do joint supplements for dogs’ work?

When dosed at the correct level, Yes! In fact, we're so confident our supplements work for dogs with existing issues, that we offer a guarantee with our highest specification Joint Plus Pro and Joint Plus HA products. See the difference in 6 weeks or your money back.

*Terms and conditions apply

Are joint supplements safe for dogs?

Yes. Riaflex joint supplements are formulated with high quality ingredients which are safe for dogs.

How soon will I see a difference?

Most dogs who require extra support will typically see a difference within around 2-4 weeks. However all dogs requirements differ, and we do recommend that fair representation would be 4-6 weeks of use.

Do I have to feeding a loading dose?

No. Our supplements are effective because we don’t underdose. We provide the correct daily dose level for body weight. For the best results long term our dose level remains the same continuously.